Impact of Multileaf Collimator Width on Dose Distribution in HyperArc Fractionated Stereotactic Irradiation for Multiple (-) Brain Metastases

Background/Aim: To assess the impact of the width of multileaf collimator (MLC) on dose distributions on HyperArc fractionated stereotactic irradiation for multiple (5-10) brain metastases. Patients and Methods: Twenty-one HyperArc (HA) plans were generated using the high definition (HD) MLC (2.5 mm...

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Bibliographic Details
Published in:Anticancer research 2021-06, Vol.41 (6), p.3153-3159
Main Authors: Ohira, Shingo, Ueda, Yoshihiro, Kanayama, Naoyuki, Isono, Masaru, Inui, Shoki, Komiyama, Riho, Washio, Hayate, Miyazaki, Masayoshi, Koizumi, Masahiko, Teshima, Teruki, Konishi, Koji
Format: Article
Language:English
Subjects:
Brain
Brain cancer
Brain stem
Collimators
Conformity
High definition
Irradiation
Metastases
Metastasis
Organs
Parameters
Radiation
Retina
Statistical analysis
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Summary:Background/Aim: To assess the impact of the width of multileaf collimator (MLC) on dose distributions on HyperArc fractionated stereotactic irradiation for multiple (5-10) brain metastases. Patients and Methods: Twenty-one HyperArc (HA) plans were generated using the high definition (HD) MLC (2.5 mm) to deliver 30-35 Gy in 3-5 fractions (HA-HD). The HyperArc plans using Millennium (ML) MLC (5 mm) were retrospectively generated (HA-ML) using the same planning parameters with HA-HD. Dosimetric parameters between the planning target volume (PTV) and organs at risk (OARs) were compared. Results: The conformity index was significantly higher (p
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.15101