Clinical Outcomes of Implantable Cardioverter-Defibrillator in Pediatric Patients　― A Korean Multicenter Study

Background:Implantable cardioverter-defibrillator (ICD) therapy is important for the prevention of sudden cardiac death, but data on clinical outcomes of ICD therapy in Asian pediatric patients are scarce. The aim of this Korean multicenter study was to evaluate the current state and elucidate the c...

Full description

Saved in:
Bibliographic Details
Published in:Circulation Journal 2021/07/21, Vol.85(8), pp.1356-1364
Main Authors: Song, Mi Kyoung, Uhm, Jae-Sun, Baek, Jae Suk, Yoon, Ja Kyoung, Na, Jae Yoon, Yu, Hee Tae, Yang, Ji-Hyuk, Oh, Seil, Park, Sang Weon, Song, Jinyoung, Huh, June, Bae, Eun-Jung
Format: Article
Language:English
Subjects:
Adolescent
Child
Congenital heart disease
Death, Sudden, Cardiac - prevention & control
Defibrillators, Implantable
Follow-Up Studies
Humans
Implantable cardioverter-defibrillator
Pediatrics
Retrospective Studies
Risk Factors
Sudden cardiac death
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background:Implantable cardioverter-defibrillator (ICD) therapy is important for the prevention of sudden cardiac death, but data on clinical outcomes of ICD therapy in Asian pediatric patients are scarce. The aim of this Korean multicenter study was to evaluate the current state and elucidate the clinical outcomes of ICD therapy in children.Methods and Results:Data from 5 pediatric cardiology centers were retrospectively collected from 2007 to 2019. Altogether, 99 patients were enrolled (mean age 13.9±4.1 years). The most common underlying disease was a primary electrical disease (56%). An ICD was implanted for primary prevention in 19%. Appropriate shock occurred in 44% of patients at a median of 1.6 years after implantation. There was no significant difference in the appropriate shock rate between patients with primary and secondary prevention indications (32% vs. 48%, respectively). A total of 33 patients (33%) experienced inappropriate shock, which was associated with primary electrical disease and follow-up duration on multivariate analysis. 17% of patients had ICD-related complications.Conclusions:The utilization rate of ICD for primary prevention was still low in the pediatric population in Korea, but there was a substantial rate of appropriate shock in these patients. Efforts to increase ICD usage to save the lives of high-risk patients and reduce the incidence of inappropriate shock are required.
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-20-0468