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Cognitive and emotional variables predicting treatment outcome of cognitive behavior therapies for patients with medically unexplained symptoms: A meta-analysis

Cognitive behavior therapy (CBT) is the best-evaluated psychological approach to treat patients with medically unexplained symptoms (MUS). We still need a better understanding of what characterizes patients with MUS who benefit more or less from CBT. This systematic review aimed to identify patients...

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Published in:Journal of psychosomatic research 2021-07, Vol.146, p.110486-110486, Article 110486
Main Authors: Sarter, Lena, Heider, Jens, Kirchner, Lukas, Schenkel, Sandra, Witthöft, Michael, Rief, Winfried, Kleinstäuber, Maria
Format: Article
Language:English
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Summary:Cognitive behavior therapy (CBT) is the best-evaluated psychological approach to treat patients with medically unexplained symptoms (MUS). We still need a better understanding of what characterizes patients with MUS who benefit more or less from CBT. This systematic review aimed to identify patients' cognitive-emotional characteristics predicting the outcome of CBT for MUS. A systematic literature search (PubMed, PsycINFO, Web of Science) revealed 37 eligible studies, 23 of these provided data for meta-analyses. Mean correlation coefficients between predictor variables and the outcomes (symptom intensity, physical or social-emotional functioning) were calculated using a random-effects model. Differences between syndromes of MUS were investigated with moderator analyses. Meta-analyses showed that patients with a comorbid mood disorder (r = 0.32, p 
ISSN:0022-3999
1879-1360
DOI:10.1016/j.jpsychores.2021.110486