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Sleeve gastrectomy prior to liver transplantation is superior to medical weight loss in reducing posttransplant metabolic complications
Strategies to optimize the management of obesity‐related metabolic complications after liver transplantation (LT) are needed. We examined the effect of pre‐LT sleeve gastrectomy (SG), as compared to medical weight loss (MWL), on post‐LT outcomes. This is a cohort study of adults (≥18 years) with med...
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Published in: | American journal of transplantation 2021-10, Vol.21 (10), p.3324-3332 |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Strategies to optimize the management of obesity‐related metabolic complications after liver transplantation (LT) are needed. We examined the effect of pre‐LT sleeve gastrectomy (SG), as compared to medical weight loss (MWL), on post‐LT outcomes. This is a cohort study of adults (≥18 years) with medically complicated obesity who were eligible for pre‐LT SG and underwent LT from January 1, 2006 to June 1, 2016. Logistic regression models evaluated the association of SG on post‐LT diabetes and hypertension, defined as new‐onset or progressive disease post‐LT. Cox regression models evaluated the association of SG on recurrent and de novo nonalcoholic fatty liver disease (NAFLD). Among 70 LT recipients who were eligible for pre‐LT SG, 14 (20%) underwent SG and 56 (80%) underwent MWL only. Mean follow‐up was 5.2 years post‐LT. The SG cohort sustained higher % total body weight loss at 3 years post‐LT (28.9% vs. 5.4%, p |
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ISSN: | 1600-6135 1600-6143 |
DOI: | 10.1111/ajt.16583 |