Adipocytokine and appetite-regulating hormone response to weight loss in adolescents with obesity: Impact of weight loss magnitude

The aim of this study was to investigate the association between the magnitude of weight loss (WL) and serum concentrations of the main adipocytokines and appetite-regulating hormones in adolescents with obesity. After completion of informed consent,108 adolescents with obesity (14–19 y of age; post...

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Bibliographic Details
Published in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2021-07, Vol.87-88, p.111188-111188, Article 111188
Main Authors: Kravchychyn, Ana Claudia Pelissari, Campos, Raquel Munhoz da Silveira, Oliveira e Silva, Luciana, Ferreira, Yasmin Alaby Martins, Corgosinho, Flávia Campos, Masquio, Deborah Cristina Landi, Vicente, Sofia Emanuelle de Castro Ferreira, Oyama, Lila Missae, Tock, Lian, de Mello, Marco Túlio, Tufik, Sérgio, Thivel, David, Dâmaso, Ana Raimunda
Format: Article
Language:English
Subjects:
Adipocytokine
Adolescents
Aerobics
Appetite
Body composition
Body fat
Body mass index
Body weight
Body weight loss
Energy
Energy balance
Exercise
Fat loss
Food
Generalized linear models
Hormones
Informed consent
Interdisciplinary aspects
Interdisciplinary therapy
Intervention
Investigations
Leptin
Mathematical models
Melanocyte-stimulating hormone
Metabolism
Neuropeptide Y
Neuropeptides
Nutrition therapy
Obesity
Physical exercise
Physical fitness
Physical therapy
Plasma levels
Statistical analysis
Teenagers
Weight control
Weight loss
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Summary:The aim of this study was to investigate the association between the magnitude of weight loss (WL) and serum concentrations of the main adipocytokines and appetite-regulating hormones in adolescents with obesity. After completion of informed consent,108 adolescents with obesity (14–19 y of age; postpubertal) were submitted to clinical, nutritional, psychological, physical exercise, and physiotherapy support for 1 y. Body composition (BC) and plasma levels of neuropeptides (neuropeptide Y [NPY], agouti-related peptide [AgRP], and α-melanocyte-stimulating hormone [α-MSH]) and leptin were measured at baseline and post-intervention. After therapy, adolescents who lost
ISSN:0899-9007
1873-1244
DOI:10.1016/j.nut.2021.111188