Cauda equina paragangliomas express HOXB13

HOXB13 is expressed in the tail bud of the developing embryo as well as in cauda equina paragangliomas and in myxopapillary ependymomas. In contrast, pheochromocytomas and paraganglioma in other locations as well as many other tumors occuring in spinal cord regions are negative.

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Bibliographic Details
Published in:Neuropathology and applied neurobiology 2021-10, Vol.47 (6), p.889-890
Main Authors: Bockmayr, Michael, Körner, Meik, Schweizer, Leonille, Schüller, Ulrich
Format: Article
Language:English
Subjects:
Animals
Cauda Equina - pathology
Central Nervous System Neoplasms - diagnosis
Central Nervous System Neoplasms - genetics
Central Nervous System Neoplasms - pathology
Diagnosis, Differential
Homeodomain Proteins - metabolism
Mice
Neuroendocrine tumors
Paraganglioma
Paraganglioma - diagnosis
Paraganglioma - genetics
Paraganglioma - pathology
Spinal cord
Tumors
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Description
Summary:HOXB13 is expressed in the tail bud of the developing embryo as well as in cauda equina paragangliomas and in myxopapillary ependymomas. In contrast, pheochromocytomas and paraganglioma in other locations as well as many other tumors occuring in spinal cord regions are negative.
ISSN:0305-1846
1365-2990
DOI:10.1111/nan.12713