Beneficial effect of Chlorella pyrenoidosa drink on healthy subjects: A randomized, placebo‐controlled, double‐blind, cross‐over clinical trial

The current study aims to explore the anti‐inflammatory activity of Chlorella pyrenoidosa on RAW 267.4 cells and followed by a cross‐over clinical trial in healthy subjects to check the antioxidant and anti‐aging properties of Chlorella water extract (CWE). For the clinical trial, 44 healthy subject...

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Bibliographic Details
Published in:Journal of food biochemistry 2021-04, Vol.45 (4), p.e13665-n/a
Main Authors: Chiu, Hui‐Fang, Lee, Hsiao‐Ju, Han, Yi‐Chun, Venkatakrishnan, Kamesh, Golovinskaia, Oksana, Wang, Chin‐Kun
Format: Article
Language:English
Subjects:
aging
antioxidant
anti‐inflammatory
Chlorella pyrenoidosa
oxidative stress
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Summary:The current study aims to explore the anti‐inflammatory activity of Chlorella pyrenoidosa on RAW 267.4 cells and followed by a cross‐over clinical trial in healthy subjects to check the antioxidant and anti‐aging properties of Chlorella water extract (CWE). For the clinical trial, 44 healthy subjects were requested to consume 27 ml of either placebo or CWE for 90 days (phase I) and vice‐versa manner for 90 days (phase II) with 4 weeks of washout period. The RAW 264.7 macrophages treated with Chlorella display potent anti‐inflammatory activity by significantly downregulating (p 
ISSN:0145-8884
1745-4514
DOI:10.1111/jfbc.13665