Diagnostic performance of the Kaiser score for characterizing lesions on breast MRI with comparison to a multiparametric classification system

•The Kaiser score has high diagnostic accuracy in breast magnetic resonance imaging.•The interobserver agreement for the Kaiser score was excellent.•The use of the Kaiser score may reduce the biopsy rate for true negative lesions. To determine the diagnostic performance of the Kaiser score and to co...

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Bibliographic Details
Published in:European journal of radiology 2021-05, Vol.138, p.109659-109659, Article 109659
Main Authors: Istomin, Aleksandr, Masarwah, Amro, Vanninen, Ritva, Okuma, Hidemi, Sudah, Mazen
Format: Article
Language:English
Subjects:
BI-RADS
Breast - diagnostic imaging
Breast cancer
Breast Neoplasms - diagnostic imaging
Humans
Magnetic Resonance Imaging
Multiparametric MRI
Radiography
Reproducibility of Results
Retrospective Studies
ROC Curve
Scoring system
Sensitivity and Specificity
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Summary:•The Kaiser score has high diagnostic accuracy in breast magnetic resonance imaging.•The interobserver agreement for the Kaiser score was excellent.•The use of the Kaiser score may reduce the biopsy rate for true negative lesions. To determine the diagnostic performance of the Kaiser score and to compare it with the BI-RADS–based multiparametric classification system (MCS). Two breast radiologists, blinded to the clinical and pathological information, separately evaluated a database of 499 consecutive patients with structural 3.0 T breast MRI and 697 histopathologically verified lesions. The Kaiser scores and corresponding MCS categories were recorded. The sensitivity and specificity of the Kaiser score and the MCS categories to differentiate benign from malignant lesions were calculated. The interobserver reproducibility and receiver operating characteristic (ROC) parameters were analysed. The sensitivity and specificity of the MCS were 100 % and 12 %, respectively, and those of the Kaiser score were 98.5 % and 34.8 % for reader 1 and 98.7 % and 47.5 % for reader 2. The area under the ROC-curve was 85.9 and 87.6 for readers 1 and 2. The interobserver intraclass correlation coefficient was excellent at 0.882. Reader 1 upgraded six lesions from BI-RADS 3 to a Kaiser score of >4, and reader 2 upgraded seven lesions. When applying the Kaiser score to 158 benign lesions readers 1 and 2 would have reduced the biopsy rate by 22.8 % and 35.4 %, respectively. The Kaiser score showed high diagnostic accuracy with excellent interobserver reproducibility. The MCS had perfect sensitivity but low specificity. Although the Kaiser score had slightly lower sensitivity, its specificity was 3–4 times greater than that of the MCS. Thus, the Kaiser score has the potential to considerably reduce the biopsy rate for true negative lesions.
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2021.109659