No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males

Plant-derived proteins have been suggested to have less anabolic properties when compared with animal-derived proteins. Whether blends of plant- and animal-derived proteins can compensate for their lesser anabolic potential has not been assessed. The present study compares post-prandial muscle prote...

Full description

Saved in:
Bibliographic Details
Published in:British journal of nutrition 2021-12, Vol.126 (12), p.1832-1842
Main Authors: Pinckaers, Philippe J.M., Kouw, Imre W.K., Hendriks, Floris K., van Kranenburg, Janneau M.X., de Groot, Lisette C.P.G.M., Verdijk, Lex. B., Snijders, Tim, van Loon, Luc J.C.
Format: Article
Language:English
Subjects:
Amino acids
Biopsy
Blood pressure
Body composition
Dietary Proteins - metabolism
Double-Blind Method
Eating
Exercise
Human and Clinical Nutrition
Humans
Ingestion
Male
Males
Mens health
Milk
Milk Proteins - metabolism
Muscle Proteins - metabolism
Muscle, Skeletal - metabolism
Muscles
Nutrition research
Phenylalanine
Physical fitness
Plants
Plasma
Postprandial Period
Protein biosynthesis
Protein synthesis
Proteins
Triticum
Wheat
Young Adult
Young adults
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Plant-derived proteins have been suggested to have less anabolic properties when compared with animal-derived proteins. Whether blends of plant- and animal-derived proteins can compensate for their lesser anabolic potential has not been assessed. The present study compares post-prandial muscle protein synthesis rates following the ingestion of milk protein with wheat protein or a blend of wheat plus milk protein in healthy, young males. In a randomised, double-blind, parallel-group design, 36 males (23 (sd 3) years) received a primed continuous L-[ring-13C6]-phenylalanine infusion after which they ingested 30 g milk protein (MILK), 30 g wheat protein (WHEAT) or a 30 g blend combining 15 g wheat plus 15 g milk protein (WHEAT+MILK). Blood and muscle biopsies were collected frequently for 5 h to assess post-prandial plasma amino acid profiles and subsequent myofibrillar protein synthesis rates. Ingestion of protein increased myofibrillar protein synthesis rates in all treatments (P < 0·001). Post-prandial myofibrillar protein synthesis rates did not differ between MILK v. WHEAT (0·053 (sd 0·013) v. 0·056 (sd 0·012) %·h−1, respectively; t test P = 0·56) or between MILK v. WHEAT+MILK (0·053 (sd 0·013) v. 0·059 (sd 0·025) %·h−1, respectively; t test P = 0·46). In conclusion, ingestion of 30 g milk protein, 30 g wheat protein or a blend of 15 g wheat plus 15 g milk protein increases muscle protein synthesis rates in young males. Furthermore, muscle protein synthesis rates following the ingestion of 30 g milk protein do not differ from rates observed after ingesting 30 g wheat protein or a blend with 15 g milk plus 15 g wheat protein in healthy, young males.
ISSN:0007-1145
1475-2662
DOI:10.1017/S0007114521000635