Intraoperative hypotension and perioperative acute ischemic stroke in patients having major elective non-cardiovascular non-neurological surgery

Purpose The association between intraoperative hypotension and perioperative acute ischemic stroke is not well described. We hypothesized that intraoperative hypotension would be associated with perioperative acute ischemic stroke. Methods Four-year retrospective cohort study of elective non-cardiov...

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Bibliographic Details
Published in:Journal of anesthesia 2021-04, Vol.35 (2), p.246-253
Main Authors: Mazzeffi, Michael, Chow, Jonathan H., Anders, Megan, Gibbons, Miranda, Okojie, Uwagbale, Feng, Amber, Ibrahim, Ikeoluwapo, Morris, Nicholas A., Martz, Douglas, Rock, Peter
Format: Article
Language:English
Subjects:
Anesthesiology
Atrial fibrillation
Brain Ischemia - epidemiology
Comorbidity
Comparative analysis
Coronary heart disease
Critical Care Medicine
Diabetes
Emergency Medicine
Humans
Hypertension
Hypotension - complications
Hypotension - epidemiology
Intensive
Ischemia
Ischemic Stroke
Medicine
Medicine & Public Health
Original Article
Pain Medicine
Postoperative Complications
Retrospective Studies
Risk Factors
Smoking
Stroke (Disease)
Stroke - epidemiology
Stroke - etiology
Stroke patients
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Summary:Purpose The association between intraoperative hypotension and perioperative acute ischemic stroke is not well described. We hypothesized that intraoperative hypotension would be associated with perioperative acute ischemic stroke. Methods Four-year retrospective cohort study of elective non-cardiovascular, non-neurological surgical patients. Characteristics of patients who had perioperative acute ischemic stroke were compared against those of patients who did not have acute ischemic stroke. Multivariable logistic regression was used to determine whether hypotension was independently associated with increased odds of perioperative acute ischemic stroke. Results Thirty-four of 9816 patients (0.3%) who met study inclusion criteria had perioperative acute ischemic stroke. Stroke patients were older and had more comorbidities including hypertension, coronary artery disease, diabetes mellitus, active tobacco use, chronic obstructive pulmonary disease, cerebral vascular disease, atrial fibrillation, and peripheral vascular disease (all P  
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-021-02901-3