Emerging roles of the CBL-CIPK calcium signaling network as key regulatory hub in plant nutrition

Plant physiology and development essentially depend on sufficient uptake of various essential nutritive ions via their roots and their appropriate transport and distribution within the organism. Many of these essential nutrients are heterogeneously distributed in the soil or are available in fluctua...

Full description

Saved in:
Bibliographic Details
Published in:Journal of plant physiology 2021-02, Vol.257, p.153335-153335, Article 153335
Main Authors: Dong, Qiuyan, Bai, Bowen, Almutairi, Bader O., Kudla, Jörg
Format: Article
Language:English
Subjects:
AKT1 protein
Ca2+ signaling
Calcium ions
Calcium signalling
CBL
Cbl protein
CIPK
Essential nutrients
Fluctuations
Homeostasis
Ions
Iron
Kinases
Magnesium
Nitrate
Nitrogen
Nutrient uptake
Nutrients
Nutrition
Phosphorylation
Plant nutrition
Plant physiology
Potassium
Protein kinase
Regulation
Signaling
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Plant physiology and development essentially depend on sufficient uptake of various essential nutritive ions via their roots and their appropriate transport and distribution within the organism. Many of these essential nutrients are heterogeneously distributed in the soil or are available in fluctuating concentrations. This natural situation requires constant regulatory adjustment and balancing of nutrient uptake and homeostasis. Here, we review recent findings on the role of Ca2+ signals and Ca2+-dependent regulation via the CBL-CIPK Ca2+ sensor-protein kinase network in these processes. We put special emphasis on Ca2+ controlled processes that contribute to establishing the homeostasis of macro-nutrients like potassium (K+), nitrogen (N), and magnesium (Mg2+) and on the micro-nutrient iron (Fe). Increasing experimental evidence indicates the occurrence of nutrient-specific, spatially and temporally defined cytoplasmic Ca2+ elevations as early responses to nutrient fluctuations. Specific CBL-CIPK complexes translate these signals into phosphorylation regulation of important channels and transporters like AKT1, NPF6.3/NRT1.1, AMT1, SLAC1, TPK1 and IRT1. We discuss a crucial and coordinating role for these Ca2+ signaling mechanisms in regulating the sensing, uptake, distribution and storage of various ions. Finally, we reflect on the emerging multifaceted and potentially integrating role of the “nutrient” kinase CIPK23 in regulating multiple nutrient responses. From this inventory, we finally deduce potential mechanisms that can convey the coordinated regulation of distinct steps in the transport of one individual ion and mechanisms that can bring about the integration of adaptive responses to fluctuations of different ions to establish a faithfully balanced plant nutrient homeostasis.
ISSN:0176-1617
1618-1328
DOI:10.1016/j.jplph.2020.153335