An audit of brain tumor patients treated in 5 years at a single institute: Our regional cancer center experience

Introduction: Brain tumors constitute a small presentation of all cancers (1.4%) and cancer related deaths (2.5%). Most of the brain tumors are malignant and carry bad prognosis and even if those which are benign still can interfere with brain functions that are required for daily living. We did an...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2020-10, Vol.16 (6), p.1466-1469
Main Authors: Patel, Pooja, Bhattacharya, Jigna, Vyas, Rakesh, Suryanarayana, Unnikrishnan
Format: Article
Language:English
Subjects:
Adult
Age Factors
Biopsy
Brain - diagnostic imaging
Brain - pathology
Brain cancer
Brain Neoplasms - diagnosis
Brain Neoplasms - epidemiology
Brain Neoplasms - mortality
Brain Neoplasms - therapy
Cancer Care Facilities - statistics & numerical data
Female
Follow-Up Studies
Humans
Incidence
India - epidemiology
Male
Medical prognosis
Neoplasm Grading
Neoplasm Recurrence, Local - epidemiology
Prognosis
Radiation therapy
Retrospective Studies
Risk Factors
Sex Distribution
Sex Factors
Survival Rate
Tumors
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Summary:Introduction: Brain tumors constitute a small presentation of all cancers (1.4%) and cancer related deaths (2.5%). Most of the brain tumors are malignant and carry bad prognosis and even if those which are benign still can interfere with brain functions that are required for daily living. We did an audit of brain tumor patients treated in our center and see their prognosis in correlation with different histological types. Materials and Methods: We analyzed 497 patients treated at our center from June 2007 to June 2012 of different histological types. All the patients underwent complete central nervous system examination and thorough workup including hematological investigations, radiological investigations, and confirmation of histological type by biopsy. These patients were then treated with surgery followed by radiotherapy or upfront curative radiotherapy as per staging and then kept on regular follow-up as per institutional protocol. Results: Majority of patients were astrocytomas (309 patients) followed by a pituitary adenoma (39 patients), oligodendroglioma (33 patients), medulloblastoma (22 patients), arteriovenous malformations (19 patients), craniopharyngioma (16 patients), and recurrent brain tumors (12 patients). There were few cases of central nervous lymphoma, meningioma, melanocytoma, ependymomas, schwannomas, hemangiopericytoma, gliosarcoma, and primitive neuroectodermal tumor. The histological types vary differently regarding presentation, treatment, and prognosis. Conclusion: Astrocytomas are the most common tumors in presentation (309 patients) in which the high-grade astrocytomas carried worse prognosis. Benign tumors such as pituitary adenomas, schwannomas, and craniopharyngiomas had the best prognosis with survival seen up to almost last follow-up.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.JCRT_202_18