Support for increased cardiovascular risk in non‐segmental vitiligo among Egyptians: A hospital‐based, case–control study

Background Data have been accumulating in the past few years that identify vitiligo as a disorder with systemic implications. Results and methods In this hospital‐based, cross‐sectional, case–control study, 50 patients with non‐segmental vitiligo and 50 age‐ and sex‐matched controls underwent analys...

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Bibliographic Details
Published in:Pigment cell and melanoma research 2021-05, Vol.34 (3), p.598-604
Main Authors: Azzazi, Yousra, Mostafa, Wedad Z., Sayed, Khadiga S., Alhelf, Maha, Safwat, Miriam, Mahrous, Ayman, El Lawindi, Mona, Ragab, Nanis
Format: Article
Language:English
Subjects:
Adult
Antioxidants
Arteriosclerosis
Atherosclerosis
Atherosclerosis - epidemiology
Atherosclerosis - etiology
Atherosclerosis - metabolism
Atherosclerosis - pathology
Biomarkers
Biomarkers - metabolism
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - pathology
cardiovascular risk
Carotid Intima-Media Thickness
Case-Control Studies
Cross-Sectional Studies
Dyslipidemia
Egypt - epidemiology
Female
Health risks
Heart Disease Risk Factors
Humans
Hydrogen peroxide
Hypercholesterolemia
Lipids
Lipids - analysis
Low density lipoprotein
Male
Malondialdehyde
Metabolic disorders
Oxidative Stress
Patients
Plaques
Risk
Vitiligo
Vitiligo - complications
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Summary:Background Data have been accumulating in the past few years that identify vitiligo as a disorder with systemic implications. Results and methods In this hospital‐based, cross‐sectional, case–control study, 50 patients with non‐segmental vitiligo and 50 age‐ and sex‐matched controls underwent analysis of serum lipid profile, oxidative stress biomarkers and carotid duplex. Hydrogen peroxide (H2O2) and malondialdehyde (MDA) were significantly higher in patients than controls (p‐value 
ISSN:1755-1471
1755-148X
DOI:10.1111/pcmr.12941