Embryo Selection Based on Morphological Parameters in a Single Vitrified-Warmed Blastocyst Transfer Cycle

The process of selecting a good quality embryo to improve the pregnancy outcomes is very important. The aim of our study was to elaborate the embryo selection process in a single vitrified-warmed blastocyst transfer (VBT) cycle by analyzing pre-vitrified and post-warmed blastocyst morphological fact...

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Published in:Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2021-04, Vol.28 (4), p.1060-1068
Main Authors: Kim, Hyun Jin, Park, Jae Kyun, Eum, Jin Hee, Song, Haengseok, Lee, Woo Sik, Lyu, Sang Woo
Format: Article
Language:English
Subjects:
Embryology
Infertility: Original Article
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Reproductive Medicine
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Summary:The process of selecting a good quality embryo to improve the pregnancy outcomes is very important. The aim of our study was to elaborate the embryo selection process in a single vitrified-warmed blastocyst transfer (VBT) cycle by analyzing pre-vitrified and post-warmed blastocyst morphological factors to improve pregnancy outcomes. In this retrospective cohort study, we performed 329 single VBT cycles. The pre-vitrified and post-warmed morphological factors of all blastocysts were analyzed. Logistic regression analysis was conducted to select the independent morphological factor associated with ongoing pregnancy. The expansion of blastocoel (mid blastocoel; aOR 2.27, 95% CI.0.80–6.42, p  = 0.12, expanded blastocoel; aOR 3.15, 95% CI.1.18–8.44, p  = 0.02) in a pre-vitrified blastocyst and the grade of inner cell mass (ICM) (grade B; aOR 0.47, 95% CI.0.27–0.83, p  = 0.01, grade C; aOR 0.22, 95% CI 0.09–0.56 p  
ISSN:1933-7191
1933-7205
DOI:10.1007/s43032-020-00349-6