Perceived fatigue in multiple sclerosis: The importance of highlighting its impact on quality of life, social network and cognition

•51. 6 % of patients showed fatigue.•Significant differences were found between fatigued and non-fatigued patients in disability, depression, HRQoL, social network, processing speed.•The results of this study confirm the relationship between perceived fatigue and HRQoL, social network and informatio...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2020-12, Vol.199, p.106265-106265, Article 106265
Main Authors: Eizaguirre, María Bárbara, Ciufia, Natalia, Roman, María Sol, Martínez Canyazo, Carlos, Alonso, Ricardo, Silva, Berenice, Pita, Cecilia, Garcea, Orlando, Vanotti, Sandra
Format: Article
Language:English
Subjects:
Adaptation
Age
Cognition
Cognition & reasoning
Consent
Fatigue
Memory
Multiple sclerosis
Neurology
Patients
Quality of life
Questionnaires
Regression analysis
Social interactions
Social networks
Social organization
Social support
Statistical analysis
Variables
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Summary:•51. 6 % of patients showed fatigue.•Significant differences were found between fatigued and non-fatigued patients in disability, depression, HRQoL, social network, processing speed.•The results of this study confirm the relationship between perceived fatigue and HRQoL, social network and information processing speed in patients with MS.•It is relevant to study fatigue and treat it appropriately, in order to avoid psychological and social dysfunctions in patients. To study the relationship between perceived fatigue and heath related quality of life (HRQoL), social support and cognition in an Argentinean population of patients with MS (PwMS). 128 PwMS were studied, 75 women (58 %). Mean age: 40 ± 10.49 years-old, education: 14 ± 3.04, Expanded Disability Status Scale (EDSS): 2.43 ± 1.87, evolution: 10.07 ± 7.23 years. Instruments: Fatigue Severity Scale (FSS); EDSS; Beck's Depression Inventory II (BDI-II); International Quality of Life questionnaire (MusiQoL); Medical Outcomes Study Social Support Survey (MOS); BICAMS Battery, 7/24 Spatial Recall Test, Paced Auditory Serial Task (PASAT-3), Word list generation task (WLG). Sixty-six patients (51.6 %) presented fatigue. Significant differences were found between fatigued and non-fatigued patients in EDSS and BDI II (p 
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2020.106265