Fibromyalgia in patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome: prevalence and screening

Objective To explore the prevalence, clinical characteristics, and screening strategy for fibromyalgia (FM) in patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome. Methods A total of 313 patients from a cohort of 354 SAPHO patients volunteered to participate in thi...

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Bibliographic Details
Published in:Clinical rheumatology 2021-04, Vol.40 (4), p.1559-1565
Main Authors: Xiang, Yirong, Jiao, Rui, Cao, Yihan, Liang, Dongfeng, Zhang, Weihong, Yu, Yanying, Zhang, Wen, Li, Chen
Format: Article
Language:English
Subjects:
Acne
Acne Vulgaris
Acquired Hyperostosis Syndrome - complications
Acquired Hyperostosis Syndrome - diagnosis
Acquired Hyperostosis Syndrome - epidemiology
Aged
Ankylosing spondylitis
C-reactive protein
Erythrocyte sedimentation rate
Fibromyalgia
Fibromyalgia - complications
Fibromyalgia - diagnosis
Fibromyalgia - epidemiology
Humans
Hyperostosis
Medicine
Medicine & Public Health
Original Article
Osteitis
Prevalence
Pustulosis
Rheumatic diseases
Rheumatology
Synovitis
Synovitis - complications
Synovitis - diagnosis
Synovitis - epidemiology
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Summary:Objective To explore the prevalence, clinical characteristics, and screening strategy for fibromyalgia (FM) in patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome. Methods A total of 313 patients from a cohort of 354 SAPHO patients volunteered to participate in this study. Demographic, clinical and laboratory data were collected at baseline. Acute-phase reactants during the last 3 months were obtained. Patient-reported outcomes (PROs) and FM evaluation were recorded by questionnaires. Results A total of 57 (18.2%) patients met the 2016 research criteria for FM. Compared to those without FM, these patients had significantly higher visual analog scale (VAS), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) scores (all p  
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-020-05394-9