Diagnostic challenge of soft tissue extranodal Hodgkin lymphoma in core-needle biopsy: case report

Hodgkin lymphoma (HL) is an uncommon malignancy usually limited to the lymph nodes and lymphatic system while extranodal involvement is much less common than in non-Hodgkin lymphoma. The current report presents an unusual case of primary classical HL (cHL), nodular sclerosis type with mixed cellular...

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Bibliographic Details
Published in:Scottish medical journal 2021-02, Vol.66 (1), p.40-45
Main Authors: Jonjić, Nives, Valković, Toni, Vujaklija, Danijela Veljković, Ilijaš, Koviljka Matušan
Format: Article
Language:English
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Summary:Hodgkin lymphoma (HL) is an uncommon malignancy usually limited to the lymph nodes and lymphatic system while extranodal involvement is much less common than in non-Hodgkin lymphoma. The current report presents an unusual case of primary classical HL (cHL), nodular sclerosis type with mixed cellularity in buttock soft tissue of 78-year old man. Primary lymphoma of the gluteal muscle is a rare disease and primary cHL is even rarer. In addition, to this unusual extranodal presentation, the present case highlight a diagnostic challenge in fine-needle biopsy masquerading a low grade sarcoma, primarily myxoinflammatory fibrosarcoma or an inflammatory lesion. However, surgical biopsy and immunohistochemistry guided correct diagnosis that was of major interest for further successful treatment.
ISSN:0036-9330
2045-6441
DOI:10.1177/0036933020941262