Can the systemic immune inflammation index preoperatively predict nasal polyp subtypes?

Purpose Chronic rhinosinusitis with nasal polyps can be classified as eosinophilic or neutrophilic based on the major inflammatory cell type in the tissue. There is a need for predictive parameters to enable rhinologists to identify the type of nasal polyp in a patient without surgery. The aim of th...

Full description

Saved in:
Bibliographic Details
Published in:European archives of oto-rhino-laryngology 2020-11, Vol.277 (11), p.3045-3050
Main Authors: Sivrice, Mehmet Emre, Okur, Erdoğan, Yasan, Hasan, Tüz, Mustafa, Kumbul, Yusuf Çağdaş, Akın, Vural
Format: Article
Language:English
Subjects:
Chronic Disease
Eosinophils - pathology
Head and Neck Surgery
Humans
Inflammation - diagnosis
Inflammation - pathology
Medicine
Medicine & Public Health
Nasal Polyps - complications
Nasal Polyps - diagnosis
Nasal Polyps - surgery
Neurosurgery
Otorhinolaryngology
Rhinitis - complications
Rhinitis - diagnosis
Rhinitis - surgery
Rhinology
Sinusitis - complications
Sinusitis - diagnosis
Sinusitis - surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose Chronic rhinosinusitis with nasal polyps can be classified as eosinophilic or neutrophilic based on the major inflammatory cell type in the tissue. There is a need for predictive parameters to enable rhinologists to identify the type of nasal polyp in a patient without surgery. The aim of the present study was to test the predictive value of the markers of inflammation to estimate eosinophilic nasal polyps. Methods The study analyzed 299 patients who underwent sinus surgery for nasal polyps from 2012 to 2019. Patients were divided into two groups according to pathology results (eosinophilic polyps = group 1, neutrophilic polyps = group 2). The values of preoperative complete blood count, systemic immune inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio were compared. Results In our series, results of ROC analyses for both mean eosinophil count and systemic immune inflammation index were statistically significant. For the eosinophil count (AUC = 0.681, p  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-020-06174-6