Distinct risks, clinical characteristics and outcomes by age at time of HIV diagnosis

Objectives New HIV diagnoses in persons aged > 50 years (hereafter ‘older persons’) are becoming more common; the clinical features and outcomes of these older individuals are poorly described. Methods We conducted a retrospective cohort study of all new adult HIV diagnoses between October 1989 a...

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Bibliographic Details
Published in:HIV medicine 2020-09, Vol.21 (8), p.505-511
Main Authors: McMillan, JM, Gill, MJ, Rubin, LH
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adult
Age
Age Factors
Aged
AIDS
Canada
CD4 antigen
CD4 Lymphocyte Count
Diagnosis
Fatalities
Female
Health risks
Heterosexuality - statistics & numerical data
HIV
HIV Infections - diagnosis
HIV Infections - mortality
Human immunodeficiency virus
Humans
Male
Middle Aged
Mortality
older adults
Older people
Population Surveillance
potential years of life lost
Retrospective Studies
Risk analysis
Risk factors
Sex
Sexually transmitted diseases
sociodemographic data
STD
Young Adult
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Summary:Objectives New HIV diagnoses in persons aged > 50 years (hereafter ‘older persons’) are becoming more common; the clinical features and outcomes of these older individuals are poorly described. Methods We conducted a retrospective cohort study of all new adult HIV diagnoses between October 1989 and December 2019 in southern Alberta, Canada. Differences in risk for HIV acquisition and screening, sociodemographic/clinical characteristics, and causes of death were compared between individuals younger and older than 50 years at the time of diagnosis. Results New HIV diagnoses in persons > 50 years old increased from 7% in 1990 to 18% in 2019. Risk for HIV acquisition and screening reasons differed by age. Heterosexual sex (29%) was the greatest risk factor among older persons, contrasting with male same sex activity in younger persons (51%) (P 
ISSN:1464-2662
1468-1293
DOI:10.1111/hiv.12887