The Charlson Comorbidity Index: can it predict the outcome in acute kidney injury?

Purpose Comorbidity has a significant impact on the health status and treatment outcome of a patient. The Charlson comorbidity index (CCI) is a frequently used scoring system, which evaluates the prognosis based on the patient’s comorbid conditions. The aim of this study was to evaluate the usefulne...

Full description

Saved in:
Bibliographic Details
Published in:International urology and nephrology 2020-09, Vol.52 (9), p.1713-1718
Main Authors: Yalin, Serkan Feyyaz, Bakir, Alev, Trabulus, Sinan, Seyahi, Nurhan, Altiparmak, Mehmet Riza
Format: Article
Language:English
Subjects:
Acute Kidney Injury - complications
Acute Kidney Injury - mortality
Adult
Aged
Aging
Comorbidity
Emergency medical care
Female
Hemodialysis
Humans
Male
Malnutrition
Medicine
Medicine & Public Health
Middle Aged
Mortality
Multivariate analysis
Nephrology
Nephrology - Original Article
Patients
Prognosis
Retrospective Studies
Sepsis
Severity of Illness Index
Urology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose Comorbidity has a significant impact on the health status and treatment outcome of a patient. The Charlson comorbidity index (CCI) is a frequently used scoring system, which evaluates the prognosis based on the patient’s comorbid conditions. The aim of this study was to evaluate the usefulness of CCI in predicting the mortality and renal recovery in non-critically ill patients with severe AKI. Methods A total of 530 adult patients who were referred from the emergency department and underwent intermittent urgent hemodialysis (uHD) were enrolled in the study. Personal history for comorbidities were recorded and then assessed using the CCI. Results The mean CCI score was 3.3 ± 2.6. In our multivariate analysis, higher white blood cell count was associated with mortality ( p  = 0.023). The other parameters including CCI score were not found to be significantly associated with mortality excluding patients with sepsis. Moreover, the CCI was not significantly useful in the discrimination of patients with complete recovery from patients who remained dependent to dialysis. Conclusions We could not find significant association between CCI and short-term hospital mortality and renal outcome. Whereas, malnutrition, inflammation and general aging may have impact on short-term mortality among patients.
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-020-02499-7