Loading…
Does physical activity influence the association between depressive symptoms and low-grade inflammation in adults? A study of 8,048 adults
•Depressive symptoms and physical inactivity are associated with low-grade inflammation.•Physical activity influenced the association between depressive symptoms and low-grade inflammation.•Physical activity practice should be stimulated among subjects with depressive symptoms aiming to reduce cardi...
Saved in:
Published in: | Physiology & behavior 2020-09, Vol.223, p.112967-112967, Article 112967 |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | •Depressive symptoms and physical inactivity are associated with low-grade inflammation.•Physical activity influenced the association between depressive symptoms and low-grade inflammation.•Physical activity practice should be stimulated among subjects with depressive symptoms aiming to reduce cardiovascular risk.
This study investigated whether physical activity (PA) influences the association between depression risk and low-grade inflammation. This was a cross-sectional study including 8,048 adults (18-59y). Depression symptoms were evaluated with the Beck depression inventory (BDI) and physical activity through the international physical activity questionnaire. Adults with infectious and inflammatory diseases were excluded. Blood samples were collected, including high sensitivity C-reactive protein (CRP), a marker of low-grade inflammation when ≥3mg/L. Additional measures of LDL-C, HDL-C, triglycerides and fasting glucose were also determined. Sex, chronological age, tobacco smoking, alcohol drinking, body mass index, dyslipidemia, high blood pressure and fasting glucose were used as covariates. Mediation models were conducted using the procedures of Karlson Holm Breen. Adults with elevated CRP (≥3mg/L) compared to those with low CRP ( |
---|---|
ISSN: | 0031-9384 1873-507X |
DOI: | 10.1016/j.physbeh.2020.112967 |