Concise Synthesis of Phospholene and Its P‑Stereogenic Derivatives

A simple method to build phospholene derivatives has been achieved in a one-pot reaction with readily available o-alkynylaryl bromides and alkylphosphine oxides. This method is also applicable to synthesize P-stereogenic phospholenes, and the resulting chiral phosphine was utilized as a ligand for c...

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Bibliographic Details
Published in:Journal of organic chemistry 2020-11, Vol.85 (22), p.14772-14778
Main Authors: Hu, Wei, Li, Er-Qing, Duan, Zheng, Mathey, François
Format: Article
Language:English
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Summary:A simple method to build phospholene derivatives has been achieved in a one-pot reaction with readily available o-alkynylaryl bromides and alkylphosphine oxides. This method is also applicable to synthesize P-stereogenic phospholenes, and the resulting chiral phosphine was utilized as a ligand for coordination chemistry.
ISSN:0022-3263
1520-6904
DOI:10.1021/acs.joc.0c00545