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Storage of an avulsed tooth prior to replantation: A systematic review and meta‐analysis

Background/Aim It is crucial to store an avulsed tooth appropriately to preserve the viability of the periodontal ligament cells prior to replantation. The aim of this systematic review was to identify the best available evidence for the effectiveness of any technique available to laypeople for stor...

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Published in:Dental traumatology 2020-10, Vol.36 (5), p.453-476
Main Authors: De Brier, Niels, O, Dorien, Borra, Vere, Singletary, Eunice M., Zideman, David A., De Buck, Emmy, Bendall, Jason C, Berry, David C, Carlson, Jestin N, Cassan, Pascal, Chang, Wei‐Tien, Charlton, Nathan P, Djärv, Therese, Douma, Matthew, Epstein, Jonathan L, Hood, Natalie A, Markenson, David S, Meyran, Daniel, Orkin, Aaron, Sakamoto, Tetsuya, Swain, Janel M, Woodin, Jeffrey A
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Language:English
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Summary:Background/Aim It is crucial to store an avulsed tooth appropriately to preserve the viability of the periodontal ligament cells prior to replantation. The aim of this systematic review was to identify the best available evidence for the effectiveness of any technique available to laypeople for storing an avulsed tooth compared with storage in milk or saliva. Methods The following databases were searched (September 2019): Cochrane Library, MEDLINE, and Embase. Two reviewers independently considered trial eligibility, then extracted and analyzed data, and assessed the risk of bias. The certainty of the body of evidence was appraised according to the GRADE methodology. Results Out of 4118 references, 33 studies were included and reported 23 comparisons of which 10 were synthesized in a meta‐analysis. The limited evidence available favors storing an avulsed tooth in Hank's balanced salt solution (pooled SMD 2.47, 95% CI [1.59;3.34], P 
ISSN:1600-4469
1600-9657
DOI:10.1111/edt.12564