Comparison of survival outcomes in patients with metastatic papillary vs. clear-cell renal cell carcinoma: a propensity-score analysis

Background To compare survival outcomes of metastatic patients harbouring either papillary (pRCC) or clear-cell (ccRCC) renal cell carcinoma in overall population and according to treatment modality. Methods Within the Surveillance, Epidemiology and End Results database (2006–2015), we identified 68...

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Bibliographic Details
Published in:World journal of urology 2021-02, Vol.39 (2), p.461-472
Main Authors: Rosiello, Giuseppe, Palumbo, Carlotta, Knipper, Sophie, Pecoraro, Angela, Luzzago, Stefano, St-Hilaire, Pierre-Antoine, Tian, Zhe, Capitanio, Umberto, Montorsi, Francesco, Shariat, Shahrokh F., Saad, Fred, Briganti, Alberto, Karakiewicz, Pierre I.
Format: Article
Language:English
Subjects:
Epidemiology
Kidney cancer
Lymph nodes
Medicine
Medicine & Public Health
Metastases
Metastasis
Nephrectomy
Nephrology
Oncology
Original Article
Regression analysis
Renal cell carcinoma
Urology
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Summary:Background To compare survival outcomes of metastatic patients harbouring either papillary (pRCC) or clear-cell (ccRCC) renal cell carcinoma in overall population and according to treatment modality. Methods Within the Surveillance, Epidemiology and End Results database (2006–2015), we identified 6800 patients (585 papillary and 6215 clear-cell) with metastatic RCC. Propensity-score (PS) matching, Kaplan–Meier plots and multivariable Cox-regression models (CRMs) were used. Results Overall, 585 (8.6%) patients harboured pRCC. Rates of nodal metastases were higher in patients with pRCC (49.7 vs. 23.3%; p  
ISSN:0724-4983
1433-8726
DOI:10.1007/s00345-020-03187-y