Impact of Cold Ischemia Time in Clinical Outcomes in Deceased Donor Renal Transplant

Renal transplants (RTs) from deceased donors have increased in Mexico because of the high need of people with terminal kidney damage. The objective of this study is to determine the impact of cold ischemia time (CIT) on clinical outcomes in the deceased donor kidney transplant. A retrospective, obse...

Full description

Saved in:
Bibliographic Details
Published in:Transplantation proceedings 2020-05, Vol.52 (4), p.1118-1122
Main Authors: Salinas, Sandy Jazmin Fragoso, Pérez, Ramón Espinoza, López, Martha Cruz, Moreno Madrigal, Luis Guillermo, Hernández Rivera, Juan Carlos H
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Renal transplants (RTs) from deceased donors have increased in Mexico because of the high need of people with terminal kidney damage. The objective of this study is to determine the impact of cold ischemia time (CIT) on clinical outcomes in the deceased donor kidney transplant. A retrospective, observational study of deceased donor RTs performed from 2013 to 2017 in the RT unit of the CMN Siglo XXI was completed. Data were collected from 202 patient records in this period; 7 clinical outcomes were determined, and logistic regression analysis was performed with CIT and extended criteria. The statistical package SPSS version 25 was used. No risk was observed for clinical outcomes with a CIT of 1080 minutes, risk of delayed function and medical complications was observed with a CIT of 1260 minutes, and risk of surgical complications was observed with a CIT of 1309 minutes. There was a correlation of 0.556 between the Maryland classification score and post-transplant medical complications. The extended criteria are related to risk for death with an odds ratio of 6.91 (95% CI, 2.27-21.01; P = .001) CIT continues to be an extremely important factor in renal graft survival and post-transplant clinical conditions. The extended criteria represent a considerable risk of death.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2020.02.010