FASpecT/CT, A New SPECT/CT Acquisition With Higher Sensitivity and Efficiency in Radioiodine Thyroid Cancer Imaging

PURPOSEThis article demonstrates the use of a new SPECT/CT acquisition protocol in patients with differentiated thyroid cancer (DTC). METHODSSPECT/CT scans (FASpecT/CT) with fewer angle acquisitions were retrospectively reviewed in 30 DTC patients treated with radioiodine at University Hospital, San...

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Bibliographic Details
Published in:Clinical nuclear medicine 2020-05, Vol.45 (5), p.356-364
Main Authors: Phillips, William T, Kukkar, Vishal, Francis, Gary L, Gorzell, Brandon C, Cooper, Albert W, Metter, Darlene F, Lancaster, Jack L
Format: Article
Language:English
Subjects:
Adult
Aged
Female
Humans
Iodine Radioisotopes
Male
Middle Aged
Radiopharmaceuticals
Sensitivity and Specificity
Single Photon Emission Computed Tomography Computed Tomography - methods
Single Photon Emission Computed Tomography Computed Tomography - standards
Thyroid Neoplasms - diagnostic imaging
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Summary:PURPOSEThis article demonstrates the use of a new SPECT/CT acquisition protocol in patients with differentiated thyroid cancer (DTC). METHODSSPECT/CT scans (FASpecT/CT) with fewer angle acquisitions were retrospectively reviewed in 30 DTC patients treated with radioiodine at University Hospital, San Antonio, Tex, from July 2017 to March 2019. This FASpecT/CT of 12 versus 60 to 64 sampled views for convention SPECT was made possible by iterative reconstruction. RESULTSThe FASpecT/CT protocol was judged to increase lesion detection in patients with low count rates. Furthermore, in patients with higher count rates, this technique reduced the acquisition time. FASpecT/CT patient images are shown as case examples in 4 of the 30 patients reviewed. CONCLUSIONSThis FASpecT/CT acquisition in radioiodine-treated DTC offers the potential of higher sensitivity for metastatic lymph node detection in low count rates and a significant decrease in imaging time in high count rates. These advantages make SPECT/CT imaging more acceptable for patients who have difficulty with longer imaging times, to include the pediatric population.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000002978