The immune status against tetanus and diphtheria in healthcare workers in Catalonia

The objective was to investigate the immune status against tetanus and diphtheria of healthcare workers in Catalonia. A cross-sectional multicentre study was conducted in seven health centres. Blood samples were obtained, and demographic and clinical variables collected. 509 health workers were incl...

Full description

Saved in:
Bibliographic Details
Published in:Vaccine 2020-03, Vol.38 (12), p.2646-2650
Main Authors: Esteve, M., Carreras, R., Casas, I., Peña, P., Guixeras, A., Torrecillas, S., Bretau, F., Subirats, P., Alonso, A., Soldevila, N., Costa, J., Domínguez, A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Aged
Antibodies
Antibodies, Bacterial - blood
Antibodies, Bacterial - immunology
Cross-Sectional Studies
Demographic variables
Diphtheria
Diphtheria - epidemiology
Diphtheria - immunology
Diphtheria - prevention & control
Female
Health care
Health care facilities
Health facilities
Health Personnel - statistics & numerical data
Heath care workers
Humans
Immune status
Immunization, Secondary - methods
Male
Medical personnel
Middle Aged
Occupational health programme
Population
Quantitative analysis
Seroepidemiologic Studies
Seroprevalence
Spain - epidemiology
Studies
Tetanus
Tetanus - epidemiology
Tetanus - immunology
Tetanus - prevention & control
Vaccination coverage
Vaccines
Whooping cough
Workers
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective was to investigate the immune status against tetanus and diphtheria of healthcare workers in Catalonia. A cross-sectional multicentre study was conducted in seven health centres. Blood samples were obtained, and demographic and clinical variables collected. 509 health workers were included. The prevalence of protective antibodies against tetanus was 94.7% (95% CI: 92.3–96.4) overall and 85.1% (95% CI: 74.5–92.0) in workers aged ≥55 years. The prevalence of protective antibodies against diphtheria was 68.6% (95% CI: 64.3–72.5%) overall and 29.7% (95% CI: 19.9–41.6) in workers aged ≥55 years. Protection against tetanus in healthcare workers is high, but should be improved in workers aged ≥55 years. Protection against diphtheria has improved in healthcare workers over the past decade (68.6% vs 46.5%) but should be improved in all ages, especially in workers aged ≥55 years.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2020.01.076