The pretemporal trans-cavernous trans-Meckel’s trans-tentorial trans-petrosal approach: a combo skill in treating skull base meningiomas

Purpose Surgical treatments for skull base meningiomas are challenging. We found that most of these lesions (75%), despite locating at the anterior, middle or posterior fossa, could be dealt with a combo skill—the pretemporal trans-cavernous trans-Meckel’s trans-tentorial trans-petrosal approach (PC...

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Bibliographic Details
Published in:Journal of neuro-oncology 2020-02, Vol.146 (3), p.407-416
Main Authors: Chen, Shao-Ching, Lin, Chun-Fu, Liao, Chih-Hsiang, Quilis-Quesada, Vicent, Wang, Jui-To, Wang, Wei-Hsin, Hsu, Sanford P. C.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Brain cancer
Clinical Study
Female
Humans
Male
Medicine
Medicine & Public Health
Meningeal Neoplasms - surgery
Meningioma - surgery
Middle Aged
Neurology
Neurosurgical Procedures - methods
Oncology
Patients
Progression-Free Survival
Retrospective Studies
Skull
Skull Base Neoplasms - surgery
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Summary:Purpose Surgical treatments for skull base meningiomas are challenging. We found that most of these lesions (75%), despite locating at the anterior, middle or posterior fossa, could be dealt with a combo skill—the pretemporal trans-cavernous trans-Meckel’s trans-tentorial trans-petrosal approach (PCMTP), which adopted the same curvilinear skin incision as for the classic pterional approach. Our aim of this study is to validate the application of this technique in treating skull base meningiomas. Methods Patients underwent surgical intervention at our institute during 2010–2018 were retrospectively reviewed. We statistically analyzed the clinical, radiological, and pathological outcomes. Results In total, 109 patients operated with at least part of the PCMTP combo technique were included. The median follow-up time was 26.6 months. Tumor locations were categorized into: Zone I—sphenoid ridge, olfactory groove, and juxtasellar meningiomas which could be dealt with pterional approach. Zone II—clinoidal and cavernous sinus meningiomas which could be dealt with pretemporal trans-cavernous approach. Zone III—Meckel’s and Incisura meningiomas which could be dealt with trans-Meckel’s trans tentorial approach. Zone IV—petroclival menigiomas which could be dealt with trans-petrosal approach. When an extensive tumor occupied the anterior, middle, and posterior fossa, the whole combination of the PCMTP technique was applied. The mortality rate is 3.7% (4 patients). Three patients (2.8%) suffered from postoperative deterioration and required occasional assistance. The location of tumor was associated with different Simpson grade removal (p = 0.0015) and resection rate (p 
ISSN:0167-594X
1573-7373
DOI:10.1007/s11060-019-03354-1