Observational study of left ventricular global longitudinal strain in ST‐segment elevation myocardial infarction patients with extended pharmaco‐invasive strategy: A six months follow‐up study

Aims and Objectives To evaluate left ventricular (LV) function by assessment of LV global longitudinal strain (GLS) in ST‐segment elevation myocardial infarction (STEMI) patients who underwent delayed fibrinolysis and coronary intervention (extended pharmaco‐invasive strategy), since LV function is...

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Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2020-02, Vol.37 (2), p.283-292
Main Authors: Manjunath, Satvic C., Doddaiah, Balaraju, Ananthakrishna, Rajiv, Sastry, Sridhar Lakshmana, Patil, Vikram S., Devegowda, Lachikrathman, Veervhadraiah, Sumangala B., bhat, Prabhavathi, Nanjappa Manjunath, Cholenahally
Format: Article
Language:English
Subjects:
extended pharmaco‐invasive therapy
global longitudinal strain
left ventricular function
percutaneous coronary intervention
ST‐segment elevation myocardial infarction
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Summary:Aims and Objectives To evaluate left ventricular (LV) function by assessment of LV global longitudinal strain (GLS) in ST‐segment elevation myocardial infarction (STEMI) patients who underwent delayed fibrinolysis and coronary intervention (extended pharmaco‐invasive strategy), since LV function is one of the determinants of both immediate and long‐term outcomes. Methods Prospective study of consecutive STEMI patients who underwent extended pharmaco‐invasive strategy. The LV function was estimated using LV GLS at baseline and at 6 months. Results The study included eighty‐seven STEMI patients who received delayed pharmaco‐invasive therapy and coronary intervention. The primary aim of the study was to evaluate a change in LV function by assessment of GLS at 6 months as compared to baseline. Prior to PCI, LV ejection fraction was 48.08 ± 6.23% and GLS was −11.11 ± 2.99%. Procedural success was achieved in all patients. LV ejection fraction after 6 months of follow‐up increased to 53.12 ± 5.61% and the GLS improved to −13.03 ± 3.06% In comparison to baseline, there was a significant improvement in both LV ejection fraction and GLS at 6 months of follow‐up (P 
ISSN:0742-2822
1540-8175
DOI:10.1111/echo.14588