Clinical impact of successful recanalization for chronic total occlusion: insights from stress myocardial perfusion imaging

The clinical benefits of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is still controversial. The purpose of this study is to assess the quantitative therapeutic benefits of successful PCI for CTO from the clinical data acquired by myocardial perfusion imaging (MPI). Co...

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Bibliographic Details
Published in:Heart and vessels 2020-07, Vol.35 (7), p.894-900
Main Authors: Umeji, Kyoko, Kawasaki, Tomohiro, Koga, Hisashi, Orita, Yoshiya, Fukuoka, Ryota, Hirai, Keisuke, Okonogi, Taichi, Kajiyama, Kimihiro, Fukami, Yurie, Soejima, Toshiya, Yamabe, Hiroshige
Format: Article
Language:English
Subjects:
Adenosine - administration & dosage
Aged
Biomedical Engineering and Bioengineering
Cardiac Surgery
Cardiology
Chronic Disease
Computed tomography
Coronary Circulation
Coronary Occlusion - diagnostic imaging
Coronary Occlusion - physiopathology
Coronary Occlusion - therapy
Data acquisition
Exercise Test
Female
Humans
Image acquisition
Ischemia
Male
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Myocardial ischemia
Myocardial Perfusion Imaging
Occlusion
Original Article
Percutaneous Coronary Intervention
Perfusion
Photon emission
Predictive Value of Tests
Recovery of Function
Recurrence
Registries
Retrospective Studies
Single photon emission computed tomography
Stroke Volume
Tomography
Tomography, Emission-Computed, Single-Photon
Treatment Outcome
Vascular Patency
Vascular Surgery
Vasodilator Agents - administration & dosage
Ventricular Function, Left
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Summary:The clinical benefits of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is still controversial. The purpose of this study is to assess the quantitative therapeutic benefits of successful PCI for CTO from the clinical data acquired by myocardial perfusion imaging (MPI). Consecutive 42 patients, who were successfully revascularized of CTO between August 2013 and March 2018, were examined. A stress MPI was performed before CTO PCI and at follow-up, and the changes in quantitative gated and perfusion single photon emission computed tomography parameters were examined. The follow-up interval was 18 ± 9 (median 14) months, during which 36 patients were maintained patency (patent CTO), while 6 were re-occluded (R/O CTO). The reduction in the % myocardial ischemia and the improvement in the ejection fraction were significantly higher in the patent CTO group than those in the R/O CTO group (67.5 ± 37.0% vs. − 56.4 ± 84.9%, p  
ISSN:0910-8327
1615-2573
DOI:10.1007/s00380-020-01559-3