Casein Kinase 1δ Triggers Giant Ankyrin Expression

During development, neurons form growth cones and neurites, but later reduce these activities to maintain a stable architecture. In this issue of Developmental Cell, LaBella et al. demonstrate that CK1δ plays a key role in winding down developmental processes exclusively by regulating poly(A) site c...

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Bibliographic Details
Published in:Developmental cell 2020-01, Vol.52 (1), p.4-5
Main Author: Thompson-Peer, Katherine L.
Format: Article
Language:English
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Summary:During development, neurons form growth cones and neurites, but later reduce these activities to maintain a stable architecture. In this issue of Developmental Cell, LaBella et al. demonstrate that CK1δ plays a key role in winding down developmental processes exclusively by regulating poly(A) site choice to promote giant Ankyrin isoform expression. During development, neurons form growth cones and neurites, but later reduce these activities to maintain a stable architecture. In this issue of Developmental Cell, LaBella et al. demonstrate that CK1δ plays a key role in winding down developmental processes exclusively by regulating poly(A) site choice to promote giant Ankyrin isoform expression.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2019.12.012