Collagen multifilament spinning

The benefits of fiber based implants and scaffolds for tissue engineering applications are their anisotropic, highly porous, and controllable macro-, micro-, and nanostructure. Collagen is one of the most commonly used material for the fabrication of scaffolds, as this biopolymer is present in the n...

Full description

Saved in:
Bibliographic Details
Published in:Materials Science & Engineering C 2020-01, Vol.106, p.110105-110105, Article 110105
Main Authors: Tonndorf, Robert, Aibibu, Dilbar, Cherif, Chokri
Format: Article
Language:English
Subjects:
Biopolymers
Biopolymers - chemistry
Collagen
Collagen - chemistry
Collagen fibers
Crosslinking
Elastic Modulus
Extracellular matrix
Fabrication
Fiber based scaffold
Fibers
Fibrous structure
Filaments
Fineness
Glutaraldehyde
Implants
Knitting
Materials science
Mechanical properties
Modulus of elasticity
Morphology
Rheology
Scaffolds
Temperature
Tensile Strength
Tissue engineering
Wet spinning
Yarn
Yarns
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The benefits of fiber based implants and scaffolds for tissue engineering applications are their anisotropic, highly porous, and controllable macro-, micro-, and nanostructure. Collagen is one of the most commonly used material for the fabrication of scaffolds, as this biopolymer is present in the natural extracellular matrix. For textile processing and textile scaffold fabrication methods, multifilament yarns are required, however, only monofilaments can be generated by state-of-the-art collagen spinning. Hence, the research presented in here aimed at the development of a collagen multifilament wet-spinning process in reproducible quality as well as the characterization of non-crosslinked and crosslinked wet-spun multifilament yarns. Wet spun collagen yarns were comprised of 6 single filaments each having a fineness of 5 tex and a diameter of 80 μm. The tensile strength of the glutaraldehyde crosslinked yarns was 169 MPa (Young's modulus 3534 MPa) in the dry state and 40 MPa (Young's modulus 281 MPa) in the wet state. Furthermore, wet spun collagen filaments showed a characteristic fibrillar structure, which was similar the morphological structure of natural collagen fibers. The textile processing of collagen multifilament yarn was demonstrated by means of knitting technology. [Display omitted]
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2019.110105