Long-term health-related quality of life of adult patients treated with extracorporeal membrane oxygenation (ECMO): An integrative review

Background: Extracorporeal membrane oxygenation (ECMO), a rescue treatment for patients with severe pulmonary and/or cardiac dysfunction, is increasingly being used worldwide. A better understanding of long-term health-related quality of life (HRQOL) is needed. Objective: To synthesize research on l...

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Bibliographic Details
Published in:	Heart & lung 2019-11, Vol.48 (6), p.538-552
Main Authors:	Knudson, Krista A., Gustafson, Carolina M., Sadler, Lois S., Whittemore, Robin, Redeker, Nancy S., Andrews, Laura K., Mangi, Abeel, Funk, Marjorie
Format:	Article
Language:	eng
Subjects:	Adult Adults Anxiety - epidemiology Depression - epidemiology Extracorporeal membrane oxygenation Extracorporeal Membrane Oxygenation - adverse effects Extracorporeal Membrane Oxygenation - methods Health-related quality of life Humans Long-term health outcomes Quality of Life Risk Assessment Survivors - psychology
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Summary:	Background: Extracorporeal membrane oxygenation (ECMO), a rescue treatment for patients with severe pulmonary and/or cardiac dysfunction, is increasingly being used worldwide. A better understanding of long-term health-related quality of life (HRQOL) is needed. Objective: To synthesize research on long-term (at least 6 months post-ECMO) HRQOL of adults treated with ECMO. Methods: In this integrative review, we searched 3 electronic databases and did a hand search of relevant journals for articles published 2000–2019, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: Thirty-one studies, representing 913 patients treated with ECMO, were included. Long-term HRQOL was slightly better for patients treated with veno-venous ECMO than veno-arterial ECMO, and mental health outcomes tended to be better than physical ones. Survivors frequently experienced physical complications, functional limitations, anxiety, depression, and post-traumatic stress symptoms, although improvements were observed over time. Conclusions: Early identification and management of physical and mental health problems may improve HRQOL outcomes.
ISSN:	0147-9563 1527-3288