The Short-Term Effects of Roux-en-Y Gastric Bypass on Renal Excretion of Sodium and Its Association with Blood Pressure

Introduction Bariatric surgery has been shown to be effective in reducing weight and has benefits, such as lowering blood pressure. An increase in urinary sodium excretion has been suggested as a possible mechanism. This study explored changes in sodium excretion and their correlation with blood pre...

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Bibliographic Details
Published in:Obesity surgery 2020, Vol.30 (1), p.102-110
Main Authors: López-Martínez, Josue Emiliano, Chávez-Negrete, Adolfo, Rodríguez-González, Arturo Abraham, Molina-Ayala, Mario Antonio, Villanueva-Recillas, Silvia, Maravilla, Pablo, Reséndiz-Barragán, Aida Monserrat, Rentería-Palomo, Enrique, Rojano-Rodríguez, Martín Edgardo
Format: Article
Language:English
Subjects:
Blood pressure
Gastrointestinal surgery
Medicine
Medicine & Public Health
Original Contributions
Sodium
Surgery
Urine
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Summary:Introduction Bariatric surgery has been shown to be effective in reducing weight and has benefits, such as lowering blood pressure. An increase in urinary sodium excretion has been suggested as a possible mechanism. This study explored changes in sodium excretion and their correlation with blood pressure after Roux-en-Y gastric bypass. Materials and Methods This study was conducted on 28 obese participants with body mass index (BMI) of 44.54 ± 7.81 kg/m 2 who underwent gastric bypass. Before surgery and at the third and sixth months after gastric bypass, blood pressure, urinary sodium concentration, 24-hour (24-h) urinary sodium excretion, and fractional excretion of sodium were evaluated. In addition, serum sodium and potassium levels were determined. Nonparametric tests were used to analyze the data. Results Blood pressure decreased after surgery and remained at low levels over the 3- and 6-month periods. The urinary sodium concentration increased at 3 months after surgery; however, the 24-h urinary sodium excretion and urine volume decreased. Interestingly, although some associations between variables were observed, significant correlations between the 24-h urinary sodium excretion and the systolic, diastolic, and mean blood pressures were found. In addition, the urine volume was higher in the sixth month than in the third month following surgery. Conclusions In the months immediately following surgery, a low-salt and low-volume diet favors decreases in urine volume and 24-h urinary sodium excretion. In addition, in the sixth month after surgery, an association between blood pressure and 24-h urinary sodium excretion was observed.
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-019-04134-6