Immediate and short‐term effects of transcatheter device closure of large atrial septal defect in senior people

Objectives We sought to evaluate the safety and efficacy in improving cardiac function and functional capacity with device closure of large atrial septal defects (ASD) in senior adults. Background Atrial septal defect accounts for about 10% of all congenital heart disease. It still remains unclear w...

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Bibliographic Details
Published in:Congenital heart disease 2019-11, Vol.14 (6), p.939-944
Main Authors: Wang, Shihai, Pan, Jun’an, Xiao, Bei, Tang, Yongjiang, Lan, Jianjun, Zheng, Xuezhong, Yang, Chao, Xu, Dawen, Zhang, Jiyu
Format: Article
Language:English
Subjects:
Atria
Cardiac function
Electrocardiography
Heart diseases
Pulmonary arteries
Safety
Ultrasonic imaging
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Summary:Objectives We sought to evaluate the safety and efficacy in improving cardiac function and functional capacity with device closure of large atrial septal defects (ASD) in senior adults. Background Atrial septal defect accounts for about 10% of all congenital heart disease. It still remains unclear whether large ASD closure in senior people should be performed or not. Hence we aim to prospectively assess the safety and clinical status of senior patients after transcatheter closure in large ASD. Patients and interventions This was a prospective study of all patients aged over 50 years who underwent device closure of a secundum large ASD between January 2013 and January 2018. Investigations including brain natriuretic peptide level, electrocardiography, chest X‐ray, transthoracic echocardiogram, transesophageal echocardiogram, and 6‐minute walk test were performed before and at 2 days and 4 weeks and 6 months after the procedure. Results Twenty patients (median age 68 years, 10 women) had transcatheter device closure of large ASD successfully. Median ASD size was 32 mm (range 30‐39 mm). Median pulmonary artery pressure was 58 mm Hg (range 47‐67 mm Hg). At 6 months, there was a significant change in right atrium size (P 
ISSN:1747-079X
1747-0803
DOI:10.1111/chd.12844