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A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition)

Updates to the TNM classification of head and neck carcinomas, including a new p16+ oropharyngeal carcinoma algorithm and the addition of ENE (N classification) and DOI (T classification), were reviewed. Abstract A number of major modifications were made to the classification of head and neck carcin...

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Bibliographic Details
Published in:Japanese journal of clinical oncology 2019-07, Vol.49 (7), p.589-595
Main Authors: Monden, Nobuya, Asakage, Takahiro, Kiyota, Naomi, Homma, Akihiro, Matsuura, Kazuto, Hanai, Nobuhiro, Kodaira, Takeshi, Zenda, Sadamoto, Fujii, Hirofumi, Tahara, Makoto, Yokota, Tomoya, Akimoto, Tetsuo, Iwae, Shigemichi, Onitsuka, Tetsuro, Ogawa, Takenori, Okano, Susumu, Takahashi, Shunji, Shimizu, Yasushi, Yonezawa, Koichiro, Hayashi, Ryuichi
Format: Article
Language:English
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Summary:Updates to the TNM classification of head and neck carcinomas, including a new p16+ oropharyngeal carcinoma algorithm and the addition of ENE (N classification) and DOI (T classification), were reviewed. Abstract A number of major modifications were made to the classification of head and neck carcinomas in the eighth edition of the American Joint Committee on Cancer, Cancer Staging Manual and Union for International Cancer Control TNM classification of Malignant Tumors. These modifications were aimed at improving the prognosis prediction accuracy of the system. In this article, we review the new edition of the TNM classification system. Among the several changes in the new system, a separate algorithm for p16-positive oropharyngeal carcinoma was included, as were new chapters on ‘Head and Neck Skin Carcinoma’ and ‘Unknown Primary Carcinoma—Cervical Nodes.’ Changes to Tumor (T) classification were made by introducing the depth of invasion of oral carcinoma, whereas changes to Node (N) classification were made by adding extra-nodal extension. It is believed that these changes will help improve the accuracy of the system in the prediction of prognosis. However, it is necessary to verify their validity through further clinical research.
ISSN:1465-3621
1465-3621
DOI:10.1093/jjco/hyz052