Impaired heart rate variability, Valsalva and 30:15 ratio indexes are associated with reduced submaximal exercise capacity in subjects with diabetes mellitus

To assess cardiac autonomic control and its association with submaximal exercise measured using the 6-minute walk test (6MWT) in subjects with type-2 diabetes mellitus (DM2). Cardiac autonomic control was assessed using Ewing’s tests and heart rate variability (HRV) in DM2 volunteers (DG, n = 22) an...

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Published in:Diabetes research and clinical practice 2019-09, Vol.155, p.107813-107813, Article 107813
Main Authors: Bonete, Gislaine, Dias, Bruna Alice L., Leandro, Daniela A.M., Fernandes, Ana Tereza N.S.F., Pereira, Carlos Henrique, Ribeiro, Cibele Teresinha Dias, Sousa, André Gustavo Pires, Resqueti, Vanessa, Fregonezi, Guilherme A. Freitas, Dias, Fernando A. Lavezzo
Format: Article
Language:English
Subjects:
Autonomic nervous system
Diabetes complications
Diabetic neuropathies
Heart rate
Physical exercise
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Summary:To assess cardiac autonomic control and its association with submaximal exercise measured using the 6-minute walk test (6MWT) in subjects with type-2 diabetes mellitus (DM2). Cardiac autonomic control was assessed using Ewing’s tests and heart rate variability (HRV) in DM2 volunteers (DG, n = 22) and sex-, age- and body mass index-matched non-diabetic controls (CG, n = 22) before, during and after 6MWT. Before the 6MWT, DG presented lower HRV represented by reduced SDNN [median 28.9 ms2 (IQR:18.6–35.4) vs. 45.1 (IQR:39.2–62.67), p 
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2019.107813