Small molecule anion transporters display in vitro antimicrobial activity against clinically relevant bacterial strains

Highly active transmembrane anion transporters have demonstrated their activity against antibiotic-resistant and clinically relevant bacterial strains. This type of compound offers promise as a strategy to develop novel antibacterial agents.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2019-08, Vol.55 (68), p.10080-10083
Main Authors: Carreira-Barral, Israel, Rumbo, Carlos, Mielczarek, Marcin, Alonso-Carrillo, Daniel, Herran, Enara, Pastor, Marta, Del Pozo, Angel, García-Valverde, María, Quesada, Roberto
Format: Article
Language:English
Subjects:
Anions
Antibiotics
Antiinfectives and antibacterials
Antimicrobial agents
Crystallography
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Description
Summary:Highly active transmembrane anion transporters have demonstrated their activity against antibiotic-resistant and clinically relevant bacterial strains. This type of compound offers promise as a strategy to develop novel antibacterial agents.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc04304g