A comparison between the effects of flaxseed oil and fish oil supplementation on cardiovascular health in type 2 diabetic patients with coronary heart disease: A randomized, double‐blinded, placebo‐controlled trial

This study compared the effects of flaxseed and fish oil supplementation on cardiovascular risk parameters in diabetic patients with coronary heart disease. Participants were randomly allocated into three intervention groups to receive either 1,000 mg of omega‐3 fatty acids from fish oil or 1,000 mg...

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Bibliographic Details
Published in:Phytotherapy research 2019-07, Vol.33 (7), p.1943-1951
Main Authors: Raygan, Fariba, Taghizadeh, Mohsen, Mirhosseini, Naghmeh, Akbari, Elmira, Bahmani, Fereshteh, Memarzadeh, Mohammad Reza, Sharifi, Nasrin, Jafarnejad, Sadegh, Banikazemi, Zarrin, Asemi, Zatollah
Format: Article
Language:English
Subjects:
Antioxidants
Cardiovascular disease
Cardiovascular diseases
Coronary artery disease
coronary heart disease
Diabetes
Diabetes mellitus
Disease control
Fatty acids
Fish
fish oil
Fish oils
Flaxseed oil
Glutathione
Health risks
Heart diseases
Insulin
metabolic status
Oils & fats
Supplements
type 2 diabetes mellitus
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Summary:This study compared the effects of flaxseed and fish oil supplementation on cardiovascular risk parameters in diabetic patients with coronary heart disease. Participants were randomly allocated into three intervention groups to receive either 1,000 mg of omega‐3 fatty acids from fish oil or 1,000 mg of omega‐3 fatty acids from flaxseed oil or placebo (n = 30 each group) twice a day for 12 weeks. A significant reduction in insulin levels (.04) was observed following flaxseed oil and fish oil supplementation compared with the placebo. In addition, a significant reduction in high‐sensitivity C‐reactive protein (.02) was seen after flaxseed oil supplementation compared with the placebo and a significant increase in total nitrite (.001) was seen after flaxseed oil and fish oil intake compared with placebo. Additionally, a significant increase in total antioxidant capacity (p 
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.6393