Fibrin glue as an adjuvant dural sealant reduces the rate of perioperative complications in posterior fossa decompression with duraplasty: A single center experience in 165 adult Chiari I patients

•Posterior fossa decompression with duraplasty can alleviate symptoms of Chiari I Malformations.•A watertight dural closure is critical to prevent post-operative complications.•Fibrin glue dural sealant reduced the risk of postoperative complications by more than two-thirds in our series.•The use of...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2019-10, Vol.68, p.80-85
Main Authors: Galan, Diego, Monuszko, Karen, Sankey, Eric W., Zakare-Fagbamila, Rasheedat, Yang, Zidanyue, Niedzwiecki, Donna, Gottfried, Oren, Bagley, Carlos A., Krucoff, Max O.
Format: Article
Language:English
Subjects:
Cerebrospinal fluid (CSF) leak
Duraseal
Fibrin glue
Hydrogel
Pseudomeningocele
Tisseel
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Summary:•Posterior fossa decompression with duraplasty can alleviate symptoms of Chiari I Malformations.•A watertight dural closure is critical to prevent post-operative complications.•Fibrin glue dural sealant reduced the risk of postoperative complications by more than two-thirds in our series.•The use of PEG hydrogel sealant did not show a significant complication rate reduction.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2019.07.036