High openness and high extroversion are linked with better time-based prospective memory in multiple sclerosis

Background Prospective memory (PM) deficits are often reported in multiple sclerosis (MS), but their relationship with neuropsychological characteristics and personality traits remains to be explored. Objective To systematically investigate both time-based and event-based PM abilities in a sample of...

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Bibliographic Details
Published in:Journal of neurology 2019-11, Vol.266 (11), p.2665-2671
Main Authors: Raimo, Simona, Trojano, Luigi, Gaita, Mariachiara, Spitaleri, Daniele, Santangelo, Gabriella
Format: Article
Language:English
Subjects:
Adult
Cognitive ability
Emotional behavior
Extraversion, Psychological
Female
Humans
Male
Medicine
Medicine & Public Health
Memory
Memory Disorders - etiology
Memory, Episodic
Mental depression
Multiple sclerosis
Multiple Sclerosis - complications
Multiple Sclerosis - psychology
Neurology
Neuroradiology
Neurosciences
Original Communication
Personality
Personality traits
Spatial memory
Visual perception
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Summary:Background Prospective memory (PM) deficits are often reported in multiple sclerosis (MS), but their relationship with neuropsychological characteristics and personality traits remains to be explored. Objective To systematically investigate both time-based and event-based PM abilities in a sample of MS without clinically relevant disability or global cognitive decline and to explore cognitive, neuropsychiatric characteristics and personality traits associated with PM deficits. Methods Thirty-three patients with MS and 33 healthy individuals were enrolled in the study. All participants underwent a standardized measure of PM to evaluate both time-based and event-based PM. Moreover, patients with MS completed the Brief Repeatable Battery to assess cognitive functioning, the Beck Depression Inventory-II and the Dimensional Apathy Scale to assess neuropsychiatric characteristics, and the NEO Personality Inventory-3 to assess personality traits. Results Individuals with MS demonstrated impaired time-based PM compared to healthy individuals. The regression analysis showed that poor performance in time-based PM was significantly related to lower extroversion and openness traits, whereas poor performance in event-based PM was significantly related to lower visuospatial memory abilities. Conclusions Low levels of openness and extroversion traits are associated with a greater risk of developing time-based PM deficit. Therefore, personality assessment and behavioural interventions should be encouraged in MS clinical practice.
ISSN:0340-5354
1432-1459
DOI:10.1007/s00415-019-09460-4