Electrospun polycaprolactone/collagen type Ⅰnanofibers oriented patch for rotator cuff repairing

Electrospinning technique was used to manufacture polycaprolactone (PCL)/collagen typeⅠ nanofibers orientated patches and to study their physical and chemical characterization, discussing their feasibility as synthetic patches for rotator cuff repairing.OBJECTIVEElectrospinning technique was used to...

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Published in:Zhongguo xiu fu chong jian wai ke za zhi 2019-05, Vol.33 (5), p.628
Main Authors: Gao, Chao, Li, Chaoming, Xu, Yulong, Wang, Zhenyong, Li, Haojiang, Luo, Xujiang, Peng, Liqing, Zhang, Bin, Shen, Shi, Liu, Shuyun, Sui, Xiang, Guo, Quanyi, Yang, Jianhua
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Language:Chinese
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Summary:Electrospinning technique was used to manufacture polycaprolactone (PCL)/collagen typeⅠ nanofibers orientated patches and to study their physical and chemical characterization, discussing their feasibility as synthetic patches for rotator cuff repairing.OBJECTIVEElectrospinning technique was used to manufacture polycaprolactone (PCL)/collagen typeⅠ nanofibers orientated patches and to study their physical and chemical characterization, discussing their feasibility as synthetic patches for rotator cuff repairing.PCL patches were prepared by electrospinning with 10% PCL electrospinning solution (control group) and PCL/collagen typeⅠorientated nanofibers patches were prepared by electrospinning with PCL electrospinning solution with 25% collagen type Ⅰ(experimental group). The morphology and microstructure of the two patches were observed by gross and scanning electron microscopy, and the diameter and porosity of the fibers were measured; the mechanical properties of the patches were tested by uniaxial tensile t
ISSN:1002-1892
DOI:10.7507/1002-1892.201811034