Characteristics and consequences of missed gastric cancer: A multicentric cohort study

Missed gastric cancer (MGC) is poorly documented in Mediterranean populations. (1) To assess the rate, predictors and survival of MGC. (2) To compare MGC and non-MGC tumors. This is a retrospective-cohort study conducted at four centers. MGC was defined as cancer detected within three years after ne...

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Bibliographic Details
Published in:Digestive and liver disease 2019-06, Vol.51 (6), p.894-900
Main Authors: Hernanz, Nerea, Rodríguez de Santiago, Enrique, Marcos Prieto, Héctor Miguel, Jorge Turrión, Miguel Ángel, Barreiro Alonso, Eva, Rodríguez Escaja, Carlos, Jiménez Jurado, Andrea, Sierra, María, Pérez Valle, Isabel, Volpato, Nadja, García Prada, María, Nuñez-Gómez, Laura, Ríos-León, Raquel, Castaño García, Andrés, García de Paredes, Ana García, Aicart, Marta, Caminoa, Alejandra, Peñas Parcía, Beatriz, Vázquez-Sequeiros, Enrique, Albillos, Agustín
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnosis
Adenocarcinoma - mortality
Aged
Aged, 80 and over
Endoscopy, Digestive System - statistics & numerical data
Esophagogastroduodenoscopy
Female
Gastric cancer
Humans
Logistic Models
Male
Middle Aged
Missed cancer
Missed Diagnosis - statistics & numerical data
Multivariate Analysis
Retrospective Studies
Spain
Stomach Neoplasms - diagnosis
Stomach Neoplasms - mortality
Survival
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Summary:Missed gastric cancer (MGC) is poorly documented in Mediterranean populations. (1) To assess the rate, predictors and survival of MGC. (2) To compare MGC and non-MGC tumors. This is a retrospective-cohort study conducted at four centers. MGC was defined as cancer detected within three years after negative esophagogastroduodenoscopy. Gastric adenocarcinomas diagnosed between 2008–2015 were included. Patients with no follow-up were excluded. During the study period 123,395 esophagogastroduodenoscopies were performed, with 1374 gastric cancers being diagnosed (1.1%). A total of 1289 gastric cancers were finally included. The overall rate of MGC was 4.7% (61/1289, 3.7–6%). A negative esophagogastroduodenoscopy in MGC patients was independently associated with PPI therapy (p 
ISSN:1590-8658
1878-3562
DOI:10.1016/j.dld.2019.02.006