Structural characterization and biological evaluation of chemical constituents from Ilex cornuta

One new ursane-type triterpenoid (1), one new ursane-type triterpenoid glycoside (2), and one new oleanane-type triterpenoid glycoside (3), along with 20 known compounds, were isolated from the leaves of Ilex cornuta. The structures of these natural products were elucidated on the basis of detailed...

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Bibliographic Details
Published in:Journal of asian natural products research 2020-04, Vol.22 (4), p.316-328
Main Authors: Yu, Shu-Juan, Yu, Zhi-Pu, Wang, Yin-Yin, Bao, Jie, Yuan, Tao, Yu, Jin-Hai, Zhang, Hua
Format: Article
Language:English
Subjects:
antioxidant activity
Antioxidants
Aquifoliaceae
Glycosides
Ilex
Ilex cornuta
Molecular Structure
Natural products
Organic chemistry
phenolic compound
Plant Leaves
Plant Roots
Structural analysis
Sulfonic acid
Triterpenes
triterpenoid
triterpenoid saponin
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Summary:One new ursane-type triterpenoid (1), one new ursane-type triterpenoid glycoside (2), and one new oleanane-type triterpenoid glycoside (3), along with 20 known compounds, were isolated from the leaves of Ilex cornuta. The structures of these natural products were elucidated on the basis of detailed spectroscopic analyses and chemical derivation. Our biological evaluation established that selective compounds showed moderate to significant antioxidant activities in the 1,1-diphenyl-2-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) methods.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2019.1570160