On DNA transfer: The lack and difficulty of systematic research and how to do it better

•Current review and critique of DNA transfer research.•Proposals for guidelines to improve and systematize research.•Introduction of comprehensive and searchable DNA transfer database. Since DNA from touched items and surfaces (“touch DNA”) can successfully and reliably be analyzed, the question as...

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Bibliographic Details
Published in:Forensic science international : genetics 2019-05, Vol.40, p.24-36
Main Authors: Gosch, Annica, Courts, Cornelius
Format: Article
Language:English
Subjects:
DNA transfer
Forensic genetics
Touch DNA
Trace DNA
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Summary:•Current review and critique of DNA transfer research.•Proposals for guidelines to improve and systematize research.•Introduction of comprehensive and searchable DNA transfer database. Since DNA from touched items and surfaces (“touch DNA”) can successfully and reliably be analyzed, the question as to how a particular DNA containing sample came to be from where it was recovered is of increasing forensic interest and expert witnesses in court are increasingly challenged to assess for instance whether an incriminatory DNA sample matching to a suspect could have been transferred to the crime scene in an innocent manner and to guess at the probability of such an occurrence. The latter however will frequently entail expressing a subjective probability i.e. simply making a best guess from experience. There is, to the present date, an extensive and complex body of literature on primary, secondary, tertiary and even higher order DNA transfer, its possibility, plausibility, dependency on an array of variables and factors and vast numbers of permutations thereof. However, from our point of view there is a lack of systematic data on DNA transfer with existing research widely varying in quality and relevance. Our aim was, starting from a comprehensive survey of the status quo and appreciating its increasing importance, to in the first part of our review raise consciousness towards the underestimated and insufficiently accounted for complexity of DNA transfer and thus appendant research of forensic scientists serving as expert witnesses in court but also acting in the role of a journal referee to point them to areas of criticism when reviewing a manuscript on DNA transfer. In the second part, we present propositions how to systematize and integrate future research efforts concerning DNA transfer. Also, we present a searchable database providing an extensive overview of the current state of knowledge on DNA transfer, intended to facilitate the identification of relevant studies adding knowledge to a specific question and thus help forensic experts to base their opinion on a broader, more complete and more reproducible selection of studies.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2019.01.012