“Non-Touch” Vena Cava Technique as an Improvement in Combined Lung and Liver Procurement in Controlled Donation After Circulatory Death

The number of organs retrieved from donation after circulatory death (DCD) donors has continued to rise in recent years. The functional superiority of DCD organs is achieved when the lungs are perfused with cold perfusion and livers with normothermic regional perfusion (NRP). Thus, a precise surgica...

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Bibliographic Details
Published in:Transplantation proceedings 2019-01, Vol.51 (1), p.9-11
Main Authors: Caralt, M., Bello, I., Sandiumenge, A., Dopazo, C., Pando, E., Molino, J.A., Lázaro, J.L., Bilbao, I., Pont, T., Solé, J., Charco, R.
Format: Article
Language:English
Subjects:
Death
Humans
Liver Transplantation - methods
Lung Transplantation - methods
Organ Preservation - methods
Perfusion - methods
Tissue and Organ Procurement - methods
Tissue Donors - supply & distribution
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Summary:The number of organs retrieved from donation after circulatory death (DCD) donors has continued to rise in recent years. The functional superiority of DCD organs is achieved when the lungs are perfused with cold perfusion and livers with normothermic regional perfusion (NRP). Thus, a precise surgical technique is required to combine thoracic and abdominal organ procurement. The technique used at our center consists of a rapid laparotomy and middle sternotomy, then the abdominal aorta (Ao) and abdominal inferior vena cava (VC) are cannulated and the descending thoracic Ao is cross-clamped. NRP is started at that point. As a variation of previously described techniques, the thoracic vena cava is not initially clamped in order to improve the return of blood volume to the NRP circuit. The pulmonary artery is cannulated to flush the lungs and the left atrial appendage is opened for drainage. After 120 minutes, NRP perfusion is stopped and the organs are flushed with cold preservation solution. In 2016, 3 livers and 6 lungs were harvested at our center using the technique described. After a minimum follow-up of 1 year, no evidence of biliary complications was observed. The combined procurement of lungs after room temperature perfusion and liver after NRP without initial clamping of the thoracic VC is feasible, with excellent function post-transplantation. •This is one of the few studies published regarding procurement of lung and liver in DCD donors.•Our study was conducted at an established transplant center with a record of more than 1100 liver transplants and 900 lung transplants.•The technique described enables an easier, optimized procedure for simultaneous multiple organ procurement. Multiple organ procurement in DCD donors can be complex and difficult, so it is very important to have good surgical protocols.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2018.02.216