Incremental diagnostic value of whole-heart dynamic computed tomography perfusion imaging for detecting obstructive coronary artery disease

•Dynamic computed tomography (CT) perfusion allows quantification of myocardial blood flow (MBF).•CT-MBF significantly correlated with fractional flow reserve.•CT-MBF provides incremental diagnostic value for detecting obstructive coronary artery disease. This study aimed to evaluate the incremental...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cardiology 2019-05, Vol.73 (5), p.425-431
Main Authors: Nishiyama, Hikaru, Tanabe, Yuki, Kido, Teruhito, Kurata, Akira, Uetani, Teruyoshi, Kido, Tomoyuki, Ikeda, Shuntaro, Miyagawa, Masao, Mochizuki, Teruhito
Format: Article
Language:English
Subjects:
Aged
Computed tomography
Computed Tomography Angiography
Coronary artery disease
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - physiopathology
Female
Fractional flow reserve
Heart - diagnostic imaging
Heart - physiopathology
Humans
Male
Middle Aged
Myocardial blood flow
Myocardial ischemia
Myocardial Perfusion Imaging
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Dynamic computed tomography (CT) perfusion allows quantification of myocardial blood flow (MBF).•CT-MBF significantly correlated with fractional flow reserve.•CT-MBF provides incremental diagnostic value for detecting obstructive coronary artery disease. This study aimed to evaluate the incremental diagnostic value of dynamic myocardial computed tomography (CT) perfusion (CTP) imaging for detecting obstructive coronary artery disease (CAD) in comparison with coronary CT angiography (CTA). Thirty-eight patients who had undergone coronary CTA and pharmacological stress dynamic CTP before invasive coronary angiography (ICA) were selected retrospectively. Using ICA, obstructive CAD was defined as the presence of severe (≥70%) or moderate (50–69%) stenosis with fractional flow reserve (FFR)
ISSN:0914-5087
1876-4738
DOI:10.1016/j.jjcc.2018.12.006