Recent Advances in Nanozyme Research

As a new generation of artificial enzymes, nanozymes have the advantages of high catalytic activity, good stability, low cost, and other unique properties of nanomaterials. Due to their wide range of potential applications, they have become an emerging field bridging nanotechnology and biology, attr...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2019-11, Vol.31 (45), p.e1805368-n/a
Main Authors: Wang, Hui, Wan, Kaiwei, Shi, Xinghua
Format: Article
Language:English
Subjects:
Biomimetic Materials - chemistry
Catalysis
Catalytic activity
Chemical synthesis
Environmental protection
enzyme mimic
Enzymes
Enzymes - metabolism
Materials science
Medical imaging
Nanomaterials
Nanostructures - chemistry
Nanotechnology
Nanotechnology - methods
nanozymes
reactive oxygen species (ROS)
theory and mechanisms
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Summary:As a new generation of artificial enzymes, nanozymes have the advantages of high catalytic activity, good stability, low cost, and other unique properties of nanomaterials. Due to their wide range of potential applications, they have become an emerging field bridging nanotechnology and biology, attracting researchers in various fields to design and synthesize highly catalytically active nanozymes. However, the thorough understanding of experimental phenomena and the mechanisms beneath practical applications of nanozymes limits their rapid development. Herein, the progress of experimental and computational research of nanozymes on two issues over the past decade is briefly reviewed: (1) experimental development of new nanozymes mimicking different types of enzymes. This covers their structures and applications ranging from biosensing and bioimaging to therapeutics and environmental protection. (2) The catalytic mechanism proposed by experimental and theoretical study. The challenges and future directions of computational research in this field are also discussed. The experimental development of new nanozymes mimicking different types of enzymes, their applications in biosensing, bioimaging, therapeutics, and environmental protection, and the catalytic mechanisms proposed by theoretical study are reviewed.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201805368