Coronary artery calcification in patients with diabetes mellitus and advanced chronic kidney disease

INTRODUCTIONPatients with chronic kidney disease (CKD) and diabetes mellitus (DM) have high cardiovascular risk. Both conditions are related to systemic atherosclerosis and vascular calcification. The prevalence and severity of coronary artery calcification (CaC) is higher in patients with DM, regar...

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Published in:Endocrinología, diabetes y nutrición. diabetes y nutrición., 2019-05, Vol.66 (5), p.297-304
Main Authors: Cano-Megías, Marta, Bouarich, Hanane, Guisado-Vasco, Pablo, Pérez Fernández, María, de Arriba-de la Fuente, Gabriel, Álvarez-Sanz, Concepción, Rodríguez-Puyol, Diego
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Language:eng ; spa
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Summary:INTRODUCTIONPatients with chronic kidney disease (CKD) and diabetes mellitus (DM) have high cardiovascular risk. Both conditions are related to systemic atherosclerosis and vascular calcification. The prevalence and severity of coronary artery calcification (CaC) is higher in patients with DM, regardless of their renal function. Data about the long-term prognostic role of CaC in diabetic patients with CKD are scarce. MATERIAL AND METHODSWe carried out a prospective longitudinal study enrolling 137 patients with advanced CKD. A non-enhanced multislice coronary computed tomography (CT) was performed at baseline. CaC was assessed using Agatston method. Patients were stratified according to their CaC score: severe calcification group (CaCs≥400HU) and mild-moderate calcification group (CaCs
ISSN:2530-0180
DOI:10.1016/j.endinu.2018.09.003