Bacterial tannases: classification and biochemical properties

Tannin acyl hydrolases, also known as tannases, are a group of enzymes critical for the transformation of tannins. The study of these enzymes, which initially evolved in different organisms to detoxify and/or use these plant metabolites, has nowadays become relevant in microbial enzymology research...

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Bibliographic Details
Published in:Applied microbiology and biotechnology 2019-01, Vol.103 (2), p.603-623
Main Authors: de las Rivas, Blanca, Rodríguez, Héctor, Anguita, Juan, Muñoz, Rosario
Format: Article
Language:English
Subjects:
Bacteria
Biomedical and Life Sciences
Biotechnology
Classification
Cloning
Enzymes
Enzymology
Gene expression
Genetic aspects
Genetic transformation
Identification and classification
Life Sciences
Metabolites
Microbial Genetics and Genomics
Microbiology
Microorganisms
Mini-Review
Properties
Substrate specificity
Substrates
Tannase
Tannins
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Summary:Tannin acyl hydrolases, also known as tannases, are a group of enzymes critical for the transformation of tannins. The study of these enzymes, which initially evolved in different organisms to detoxify and/or use these plant metabolites, has nowadays become relevant in microbial enzymology research due to their relevant role in food tannin transformation. Microorganisms, particularly bacteria, are major sources of tannase. Cloning and heterologous expression of bacterial tannase genes and structural studies have been performed in the last few years. However, a systematic compilation of the information related to all recombinant tannases, their classification, and characteristics is missing. In this review, we explore the diversity of heterologously produced bacterial tannases, describing their substrate specificity and biochemical characterization. Moreover, a new classification based on sequence similarity analysis is proposed. Finally, putative tannases have been identified in silico for each group of tannases taking advantage of the use of the “tannase” distinctive features previously proposed.
ISSN:0175-7598
1432-0614
DOI:10.1007/s00253-018-9519-y